BKMRSTRN.RVW 980405 "The Miracle Strain", Michael Cordy, 1997, 0-688-15508-1, U$24.00/C$31.75 %A Michael Cordy %C 1350 Avenue of the Americas, New York, NY 10019 %D 1997 %G 0-688-15508-1 %I William Morrow & Co %O U$24.00/C$31.75 800-843-9389 webmaster@williammorrow.com %P 367 p. %T "The Miracle Strain" We got the old standard science versus religion schtick here, with a search for a genetic basis for you-know-what two thousand year old healer, plus a loony band of religious fanatics, and a thoroughly nasty assassin. First in the technical lineup, we have genetic research. Now, this is not my field, but I do know enough to know that the Genescope, as proposed, would not render the Human Genome Project obsolete. The point of getting a database of the genome is not simply to get a big long list of amino acids, but also to know what they mean. What happens when you replace these ones? What happens when you eliminate them? The Genescope sounds like it would make a first rate automated sequencer (de-sequencer?) and would thus be a great help in the human Genome Project, but it would never replace the project itself. By the same token, this business of genes outside of the normal sequence is difficult. A great deal of genetic material appears to have no particular purpose. (There is the standard joke that has geneticists finally decode some of this material, only to find that some great long string of codons reads "This space intentionally left blank.") The Gene Genie sounds reasonable, given a completed genome database. It could tell you hair and eye colour, height, bone structure, and genetic diseases. Wouldn't be able to give you much in the way of weight or hair style, although I suppose it could tell you whether someone had a natural wave. (Of course, this is assuming that you are trying to find an image of a man. If you've got a female set of genes, you *might* be able to determine the height.) In terms of the data security stuff, there is no relation whatsoever to reality. None. Zip. Zero. I'm sorry, you're wrong, but thanks for playing and feel free to try again sometime when our topic is "viruses." (No, on second thought, don't.) This is someone who has seen too many movies or episodes of Tekwar or has read too many books by William Gibson. We have graphical interfaces at the system level, security programs that helpfully identify themselves, no audit trails, reprogramming of system security without bringing the system down (and imposed while the cracker is yet without the gates), security software that helpfully gives you sixty seconds to rifle the vault before kicking in, and security traps that lock you into the system (and presumably cause big claws to rise out of you keyboard and grab you so that you can't pull the plug on the modem). What we *don't* have is companies in the same line of work being able to call each other and say "Bonjour, Francois, how much for a query on your database for a sequence we are looking for?" "For you, a thousand francs." "Thanks, I'll send you an email with the string in fifteen minutes." But what really struck me was a little problem of logic. Let's say we have an atheist trying to find genetic material from Jesus of Nazareth. We don't have any particular problem with relics since an atheist would not believe that Jesus rose from the dead and ascended into heaven, and therefore would not have left bits behind. (Of course, fragments of the "true cross" could be used to repopulate the Sahara Forest, but that is only a problem in sampling size.) But since an atheist does not, pretty much be definition, believe in miracles, then why go looking for genetic material in transubstantiated wafers and the bleeding from stigmata? This problem of religious topics really weakens the book severely. Cordy appears to be on the non-religious side, and gives us a reasonable, non-supernatural, if somewhat facile, explanation. (Good juju, kid. How do you get a protein to penetrate the skin and stimulate the body to repair a massive trauma within less than a minute? Never mind.) Good denouement, especially since it hoists the bad guys very much on their own petard (not to mention hubris). And then he gives us a real wimp out mystical anticlimax. copyright Robert M. Slade, 1998 BKMRSTRN.RVW 980405